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Kallikrein 1

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Cat. No. Especies Descripción del producto Estructura Pureza Característica
KL1-H52H4 Human Human Kallikrein 1 / KLK-1 (25-262) Protein, His Tag (active enzyme, HPLC verified)
KL1-H52H4-structure
KL1-H52H4-sds
KL1-H52H4-hplc
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Synonym Name

KLK1,Kallikrein-1,KLKR,Klk6

Background

Kallikrein-1 (KLK1) belongs to the peptidase S1 family and Kallikrein subfamily. KLK1 contains one peptidase S1 domain. KLK-1 preferential cleavage of Arg-|-Xaa bonds in small molecule substrates and also has highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Clinical and Translational Updates

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